Research reveals genetic link to human intelligence

10 Aug 2011

University of Manchester scientists, working with colleagues in Edinburgh and Australia, have provided the first direct biological evidence for a genetic contribution to people's intelligence.

Previous studies on twins and adopted people suggested that there is a substantial genetic contribution to thinking skills, but this new study - published in the journal Molecular Psychiatry - is the first to find a genetic contribution by testing people's DNA for genetic variations.

The team studied two types of intelligence in more than 3,500 people from Edinburgh, Aberdeen, Newcastle and Manchester. The paper, by Dr Neil Pendleton and colleagues, found that 40 per cent to 50 per cent of people's differences in these abilities could be traced to genetic differences.

The study examined more than half a million genetic markers on every person in the study.

The new findings were made possible using a new type of analysis invented by Professor Peter Visscher and colleagues in Brisbane. As well as the findings in people from Scotland and England, the team checked their results in a separate group of people from Norway.

Dr Pendleton, who led the Manchester team in the Centre for Integrated Genomic Research, said, ''This is the first reported research to examine the intelligence of healthy older adults and, using a comprehensive genetic survey, we were able to show a substantial genetic contribution in our ability to think.